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Peyote Ceremony


Peyote is a spineless cactus native to parts of Peru, Mexico, and the southwest U.S. The peyote drug is psychoactive due to the presence of mescaline, a hallucinogen found in and on the peyote cactus. Peyote is relatively rare, and for this reason, drug dealers may deceptively label LSD or PCP as mescaline in an attempt to expand their market. On the street, peyote is referred to by various names.

Peyote ceremony, Peru

Peyote Ceremony

The Peyote Ceremony is a profoundly spiritual tradition within various Native American cultures, deeply rooted in their history and beliefs. The ceremony, primarily involving the consumption of the peyote cactus, serves as a sacred conduit to the spiritual realm and is integral in community bonding, cultural identity, and traditional knowledge transmission.

Peyote itself is revered for its ability to induce significant spiritual experiences, believed to connect individuals to higher powers and the divine. Participants of the ceremony engage in various rituals and symbolic acts, including the use of sacred objects like eagle feathers, tobacco, and cornmeal. These ceremonies are usually conducted in a sacred space such as a traditional teepee or sweat lodge and are led by a knowledgeable spiritual leader, often referred to as a roadman.

The ceremonies are not just spiritual but also have a healing aspect, being used traditionally to treat physical, mental, and emotional imbalances. These healing properties are deeply respected within the communities, and the ceremonies are seen as a means to overcome issues like trauma and addiction.

However, the use of peyote has faced legal challenges and controversies, especially concerning its classification as a psychoactive substance. The Native American Church has fought for legal protection of its use in religious ceremonies, a right that has been upheld by the Supreme Court in recognition of its cultural and spiritual significance. Despite these legal protections, peyote’s conservation is an ongoing concern due to over-harvesting and habitat loss, leading to various initiatives aimed at sustainable harvesting and cultivation.

For non-Native individuals interested in the Peyote Ceremony, it’s crucial to approach with respect and understanding. Participation is often restricted to members of Native American tribes or recognized religious organizations, and it’s vital to respect the cultural protocols surrounding its use.

After Ceremony peyotel, Peru


The peyote drug is among the oldest known psychedelic substances. The Aztecs venerated it as being magical and holy. Many other Native American tribes have used peyote for medicinal purposes, such as for treating alcohol dependence. In addition, peyote has seen regular use in Native American spiritual ceremonies. Both mescaline and peyote are classified as Schedule I controlled substances in the United States. This classification means that they are considered by the U.S. government to have a high potential for abuse and no acceptable medical purposes.

Mechanism of Action

Chemically, mescaline is classified as a phenethylamine and is therefore unrelated to other psychedelics such as LSD or psilocybin mushrooms. However, it does belongs to the same category as synthetic psychedelics like ecstasy (MDMA). Peyote produces its effects by targeting norepinephrine and dopamine neurotransmitters, as mescaline is similar in structure to them. Mescaline, therefore, intervenes with normal processes in the brain that involve these two chemicals. Dopamine is a chemical in the central nervous system (CNS) responsible for feelings of reward, pleasure, and well-being. Norepinephrine is responsible for stress, and the activation and modulation of the fight-or-flight response.